منابع مشابه
Animal Models of Human Pathology
Animal models of human pathologies, including naturally occurring, induced, or engineered animals, are valuable tools for understanding the physiopathology of the disease and discovering novel therapeutic targets and drugs. In fact, although scientific research has always relied on the use of cell cultures, information that is obtained through in vitro studies can be extrapolated to the biomedi...
متن کاملAnimal Models of Human Pathology 2014
In this special issue we gather together 23 articles (15 reviews, 7 research articles, and 1 methodology report) with diverse information presently available on animal models of human disease. The use of animal for studying human diseases, from the pathogenesis to the clinical aspects of diagnosis and therapy, has always been a very useful tool and indeed, has contributed enormously to our unde...
متن کاملVisual pathology in animal prion diseases.
Prion diseases, also known as the transmissible spongiform encephalopathies (TSEs), are a group of slowly developing neurodegenerations occurring in human and animals. Prion diseases can be transferred between animals, humans, from humans to animals, and from animals to humans. As a result, the central nervous system is attacked, resulting in microglia activation, astrocytosis, prion plaque dep...
متن کاملAnimal Models of Human Pathology 2016
1 Istituto per l’Endocrinologia e l’Oncologia Sperimentale (IEOS), CNR, 80131 Naples, Italy 2Santiago University Clinical Hospital, Instituto de Investigación Sanitaria de Santiago (IDIS), 15706 Santiago de Compostela, Spain 3Human Cancer Genetics Program/CCC, The Ohio State University, Columbus, OH 43210, USA 4Department of Clinical and Molecular Medicine, Sapienza University of Rome, 00100 Ro...
متن کاملThe Ultrastructural Identity of Alzheimer's Pathology: Lessons from Animal Models
Dr. Alois Alzheimer was an accomplished histopathologist. At the time of his November 1906 lecture in Tübingen, Germany, where he presented the case of his patient Augustine D, he had spent many years in the histology lab. Four years earlier, the “Bielschowsky” silver staining method was developed and nearly a decade before Santiago Ramón y Cajal had perfected Camillo Golgi's silver staining me...
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ژورنال
عنوان ژورنال: Nature
سال: 1964
ISSN: 0028-0836,1476-4687
DOI: 10.1038/201434a0